Publications

2023

Poddar, S., Tanaka, J., Running, K. L., Kariyawasam, G. K., Faris, J. D., Friesen, T. L., Cho, M.-J., Cate, J. H., & Staskawicz, B. Optimization of highly efficient exogenous-DNA-free cas9-ribonucleoprotein mediated gene editing in disease susceptibility loci in wheat (Triticum aestivum L.). Frontiers in Plant Science, 13. 2023 Jan 10; DOI: 10.3389/fpls.2022.1084700

Karavolias, Nicholas G., Dhruv Patel-Tupper, Kyungyong Seong, Michelle Tjahjadi, Gloria-Alexandra Gueorguieva, Jaclyn Tanaka, Ana Gallegos Cruz et al. "Paralog editing tunes rice stomatal density to maintain photosynthesis and improve drought tolerance." Plant Physiology (2023): kiad183. https://doi.org/10.1093/plphys/kiad183

Michael A., Berkoff Kodiak C., Gill Baljeet K., Iavarone Anthony T., Lieberman Samantha E., Ma Jessica M., Schultink Alex, Karavolias Nicholas G., Wyman Stacia K., Chauhan Raj Deepika, Taylor Nigel J., Staskawicz Brian J., Cho Myeong-Je, Rokhsar Daniel S., Lyons Jessica B. “CRISPR-Cas9-mediated knockout of CYP79D1 and CYP79D2 in cassava attenuates toxic cyanogen production “. Frontiers in Plant Science, 2023 March 17. DOI: 10.3389/fpls.2022.1079254

Tamborski, J., Seong, K., Liu, F., Staskawicz, B., & Krasileva, K. (2023). Altering specificity and auto-activity of plant immune receptors Sr33 and Sr50 via a rational engineering approach. Molecular Plant-Microbe Interactions, (ja). 10.1094/MPMI-07-22-0154-R

2021

Thomazella D, Seong K, Mackelprang R, Dahlbeck D, Geng Y, Gill US, Qi T, Pham J, Giuseppe P, Lee CY, Ortega A, Cho MJ, Hutton SF, Staskawicz B. Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance. PNAS. 2021 July 118 (27) e2026152118; DOI: 10.1073/pnas.2026152118

2020

Martin R, Qi T, Zhang H, Liu F, King M, Toth C, Nogales E, Staskawicz BJ. Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ. Science. 2020 Dec 4;370(6521):eabd9993. PMID: 33273074. DOI: 10.1126/science.abd9993.

Poddar S, Tanaka J, Cate JHD, Staskawicz B, Cho MJ. Efficient isolation of protoplasts from rice calli with pause points and its application in transient gene expression and genome editing assays. Plant Methods. 2020 Nov 12;16(1):151. PMID: 33292393; PMCID: PMC7663885. DOI: 10.1186/s13007-020-00692-4.

Seong K, Seo E, Witek K, Li M, Staskawicz B. Evolution of NLR resistance genes with noncanonical N-terminal domains in wild tomato species. New Phytol. 2020 Sep;227(5):1530-1543. Epub 2020 May 23. PMID: 32344448. DOI: 10.1111/nph.16628.

2019

Tian W, Hou C, Ren Z, Wang C, Zhao F, Dahlbeck D, Hu S, Zhang L, Niu Q, Li L, Staskawicz BJ, Luan S. A calmodulin-gated calcium channel links pathogen patterns to plant immunity. Nature. PMID 31316205. DOI: 10.1038/s41586-019-1413-y.

Horsefield S, Burdett H, Zhang X, Manik MK, Shi Y, Chen J, Qi T, Gilley J, Lai JS, Rank MX, Casey LW, Gu W, Ericsson DJ, Foley G, Hughes RO, Bosanac T, von Itzstein M, Rathjen JP, Nanson JD, Boden M, Dry IB, Williams SJ, Staskawicz BJ, Coleman MP, Ve T, Dodds PN, Kobe B. NAD+ cleavage activity by animal and plant TIR domains in cell death pathways. Science. 2019 Aug 23;365(6455):793-799. PMID: 31439792. DOI: 10.1126/science.aax1911.

Demirer GS, Zhang H, Matos JL, Goh NS, Cunningham FJ, Sung Y, Chang R, Aditham AJ, Chio L, Cho MJ, Staskawicz B, Landry MP. High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants. Nat Nanotechnol. 2019 May;14(5):456-464. Epub 2019 Feb 25. PMID: 30804481. DOI: 10.1038/s41565-019-0382-5.

Gomez MA, Lin ZD, Moll T, Chauhan RD, Hayden L, Renninger K, Beyene G, Taylor NJ, Carrington JC, Staskawicz BJ, Bart RS. Simultaneous CRISPR/Cas9-mediated editing of cassava eIF4E isoforms nCBP-1 and nCBP-2 reduces cassava brown streak disease symptom severity and incidence. Plant Biotechnol J. 2019 Feb;17(2):421-434. Epub 2018 Oct 5. PMID: 30019807; PMCID: PMC6335076. DOI: 10.1111/pbi.12987.

Schultink A, Qi T, Bally J, Staskawicz B. Using forward genetics in Nicotiana benthamiana to uncover the immune signaling pathway mediating recognition of the Xanthomonas perforans effector XopJ4. New Phytol. 2019 Jan;221(2):1001-1009. Epub 2018 Aug 29. PMID: 30156705. DOI: 10.1111/nph.15411.

2017

Schultink A, Qi T, Lee A, Steinbrenner AD, Staskawicz B. Roq1 mediates recognition of the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1. The Plant Journal : For Cell and Molecular Biology. PMID 28891100. DOI: 10.1111/tpj.13715. P

Zhang X, Bernoux M, Bentham AR, Newman TE, Ve T, Casey LW, Raaymakers TM, Hu J, Croll TI, Schreiber KJ, Staskawicz BJ, Anderson PA, Sohn KH, Williams SJ, Dodds PN, et al. Multiple functional self-association interfaces in plant TIR domains. Proceedings of the National Academy of Sciences of the United States of America. PMID 28159890. DOI: 10.1073/pnas.1621248114.

Schwartz AR, Morbitzer R, Lahaye T, Staskawicz BJ. TALE-induced bHLH transcription factors that activate a pectate lyase contribute to water soaking in bacterial spot of tomato. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E897-E903. Epub 2017 Jan 18. PMID: 28100489; PMCID: PMC5293091. DOI: 10.1073/pnas.1620407114.

2016

Schreiber KJ, Bentham A, Williams SJ, Kobe B, Staskawicz BJ. Multiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell Death. Plos Pathogens. 12: e1005769. PMID 27427964 DOI: 10.1371/journal.ppat.1005769

Timilsina S, Abrahamian P, Potnis N, Minsavage GV, White FF, Staskawicz BJ, Jones JB, Vallad GE, Goss EM. Analysis of sequenced genomes of Xanthomonas perforans identifies candidate targets for resistance breeding in tomato. Phytopathology. PMID 27392180 DOI: 10.1094/PHYTO-03-16-0119-FI

Goritschnig S, Steinbrenner AD, Grunwald DJ, Staskawicz BJ. Structurally distinct Arabidopsis thaliana NLR immune receptors recognize tandem WY domains of an oomycete effector. The New Phytologist. PMID 26725254 DOI: 10.1111/nph.13823

2015

Cohn M, Morbitzer R, Lahaye T, Staskawicz BJ. Comparison of gene activation by two TAL effectors from Xanthomonas axonopodis pv. manihotis reveals candidate host susceptibility genes in cassava. Molecular Plant Pathology. PMID 26575863 DOI: 10.1111/mpp.12337

Gonzalez TL, Liang Y, Nguyen BN, Staskawicz BJ, Loqué D, Hammond MC. Tight regulation of plant immune responses by combining promoter and suicide exon elements. Nucleic Acids Research. PMID 26138488 DOI: 10.1093/nar/gkv65

Schwartz AR, Potnis N, Timilsina S, Wilson M, Patané J, Martins J, Minsavage GV, Dahlbeck D, Akhunova A, Almeida N, Vallad GE, Barak JD, White FF, Miller SA, Ritchie D, ... ... Staskawicz BJ, et al. Phylogenomics of Xanthomonas field strains infecting pepper and tomato reveals diversity in effector repertoires and identifies determinants of host specificity. Frontiers in Microbiology. 6: 535. PMID 26089818 DOI: 10.3389/fmicb.2015.00535

Steinbrenner AD, Goritschnig S, Staskawicz BJ. Recognition and activation domains contribute to allele-specific responses of an Arabidopsis NLR receptor to an oomycete effector protein. Plos Pathogens. 11: e1004665. PMID 25671309 DOI: 10.1371/journal.ppat.1004665

Timilsina S, Jibrin MO, Potnis N, Minsavage GV, Kebede M, Schwartz A, Bart R, Staskawicz B, Boyer C, Vallad GE, Pruvost O, Jones JB, Goss EM. Multilocus sequence analysis of xanthomonads causing bacterial spot of tomato and pepper plants reveals strains generated by recombination among species and recent global spread of Xanthomonas gardneri. Applied and Environmental Microbiology. 81: 1520-9. PMID 25527544 DOI: 10.1128/AEM.03000-14

Horvath DM, Pauly MH, Hutton SF, Vallad GE, Scott JW, Jones JB, Stall RE, Dahlbeck D, Staskawicz BJ, Tricoli D, Deynze AV. The pepper Bs2 gene confers effective field resistance to bacterial leaf spot and yield enhancement in Florida tomatoes Acta Horticulturae. 1069: 47-52.

2014

Cohn M, Bart RS, Shybut M, Dahlbeck D, Gomez M, Morbitzer R, Hou BH, Frommer WB, Lahaye T, Staskawicz BJ. Xanthomonas axonopodis virulence is promoted by a transcription activator-like effector-mediated induction of a SWEET sugar transporter in cassava. Molecular Plant-Microbe Interactions : Mpmi. 27: 1186-98. PMID 25083909 DOI: 10.1094/MPMI-06-14-0161-R

Upadhyaya NM, Mago R, Staskawicz BJ, Ayliffe MA, Ellis JG, Dodds PN. A bacterial type III secretion assay for delivery of fungal effector proteins into wheat. Molecular Plant-Microbe Interactions : Mpmi. 27: 255-64. PMID 24156769 DOI: 10.1094/MPMI-07-13-0187-FI

2013

Dangl JL, Horvath DM, Staskawicz BJ. Pivoting the plant immune system from dissection to deployment. Science (New York, N.Y.). 341: 746-51. PMID 23950531 DOI: 10.1126/science.1236011

Nekrasov V, Staskawicz B, Weigel D, Jones JD, Kamoun S. Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nature Biotechnology. 31: 691-3. PMID 23929340 DOI: 10.1038/nbt.2655

Sharlach M, Dahlbeck D, Liu L, Chiu J, Jiménez-Gómez JM, Kimura S, Koenig D, Maloof JN, Sinha N, Minsavage GV, Jones JB, Stall RE, Staskawicz BJ. Fine genetic mapping of RXopJ4, a bacterial spot disease resistance locus from Solanum pennellii LA716. Tag. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik. 126: 601-9. PMID 23117718 DOI: 10.1007/s00122-012-2004-6

2012

Steinbrenner AD, Goritschnig S, Krasileva KV, Schreiber KJ, Staskawicz BJ. Effector recognition and activation of the Arabidopsis thaliana NLR innate immune receptors. Cold Spring Harbor Symposia On Quantitative Biology. 77: 249-57. PMID 23174767 DOI: 10.1101/sqb.2012.77.014860

Horvath DM, Stall RE, Jones JB, Pauly MH, Vallad GE, Dahlbeck D, Staskawicz BJ, Scott JW. Transgenic resistance confers effective field level control of bacterial spot disease in tomato. Plos One. 7: e42036. PMID 22870280 DOI: 10.1371/journal.pone.0042036

Bart R, Cohn M, Kassen A, McCallum EJ, Shybut M, Petriello A, Krasileva K, Dahlbeck D, Medina C, Alicai T, Kumar L, Moreira LM, Rodrigues Neto J, Verdier V, Santana MA, ... ... Staskawicz BJ, et al. High-throughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance. Proceedings of the National Academy of Sciences of the United States of America. 109: E1972-9. PMID 22699502 DOI: 10.1073/pnas.1208003109

Goritschnig S, Krasileva KV, Dahlbeck D, Staskawicz BJ. Computational prediction and molecular characterization of an oomycete effector and the cognate Arabidopsis resistance gene. Plos Genetics. 8: e1002502. PMID 22359513 DOI: 10.1371/journal.pgen.1002502

Win J, Krasileva KV, Kamoun S, Shirasu K, Staskawicz BJ, Banfield MJ. Sequence divergent RXLR effectors share a structural fold conserved across plant pathogenic oomycete species. Plos Pathogens. 8: e1002400. PMID 22253591 DOI: 10.1371/journal.ppat.1002400

2011

Krasileva KV, Zheng C, Leonelli L, Goritschnig S, Dahlbeck D, Staskawicz BJ. Global analysis of Arabidopsis/downy mildew interactions reveals prevalence of incomplete resistance and rapid evolution of pathogen recognition. Plos One. 6: e28765. PMID 22194907 DOI: 10.1371/journal.pone.0028765

Leonelli L, Pelton J, Schoeffler A, Dahlbeck D, Berger J, Wemmer DE, Staskawicz B. Structural elucidation and functional characterization of the Hyaloperonospora arabidopsidis effector protein ATR13. Plos Pathogens. 7: e1002428. PMID 22194684 DOI: 10.1371/journal.ppat.1002428

Zhao B, Dahlbeck D, Krasileva KV, Fong RW, Staskawicz BJ. Computational and biochemical analysis of the Xanthomonas effector AvrBs2 and its role in the modulation of Xanthomonas type three effector delivery. Plos Pathogens. 7: e1002408. PMID 22144898 DOI: 10.1371/journal.ppat.1002408

Chou S, Krasileva KV, Holton JM, Steinbrenner AD, Alber T, Staskawicz BJ. Hyaloperonospora arabidopsidis ATR1 effector is a repeat protein with distributed recognition surfaces. Proceedings of the National Academy of Sciences of the United States of America. 108: 13323-8. PMID 21788488 DOI: 10.1073/pnas.1109791108

Potnis N, Krasileva K, Chow V, Almeida NF, Patil PB, Ryan RP, Sharlach M, Behlau F, Dow JM, Momol M, White FF, Preston JF, Vinatzer BA, Koebnik R, Setubal JC, ... ... Staskawicz BJ, et al. Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper. Bmc Genomics. 12: 146. PMID 21396108 DOI: 10.1186/1471-2164-12-146

2010

Krasileva KV, Dahlbeck D, Staskawicz BJ. Activation of an Arabidopsis resistance protein is specified by the in planta association of its leucine-rich repeat domain with the cognate oomycete effector. The Plant Cell. 22: 2444-58. PMID 20601497 DOI: 10.1105/tpc.110.075358

Moreira LM, Almeida NF, Potnis N, Digiampietri LA, Adi SS, Bortolossi JC, da Silva AC, da Silva AM, de Moraes FE, de Oliveira JC, de Souza RF, Facincani AP, Ferraz AL, Ferro MI, Furlan LR, ... ... Staskawicz BJ, et al. Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. aurantifolii. Bmc Genomics. 11: 238. PMID 20388224 DOI: 10.1186/1471-2164-11-238

Lacombe S, Rougon-Cardoso A, Sherwood E, Peeters N, Dahlbeck D, van Esse HP, Smoker M, Rallapalli G, Thomma BP, Staskawicz B, Jones JD, Zipfel C. Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance. Nature Biotechnology. 28: 365-9. PMID 20231819 DOI: 10.1038/nbt.1613

Catanzariti AM, Dodds PN, Ve T, Kobe B, Ellis JG, Staskawicz BJ. The AvrM effector from flax rust has a structured C-terminal domain and interacts directly with the M resistance protein. Molecular Plant-Microbe Interactions : Mpmi. 23: 49-57. PMID 19958138 DOI: 10.1094/MPMI-23-1-0049

Catanzariti AM, Dodds PN, Ellis JG, Staskawicz BJ. The interaction of avirulence and resistance gene products in flax rust disease - Providing advances in rust research Canadian Journal of Plant Pathology. 32: 11-19. DOI: 10.1080/07060661003621068

2009

Staskawicz B. First insights into the genes that control plant-bacterial interactions. Mol Plant Pathol. 2009 Nov;10(6):719-20. doi: 10.1111/j.1364-3703.2009.00584.x. PMID: 19849779; PMCID: PMC6640470.

Liu J, Elmore JM, Fuglsang AT, Palmgren MG, Staskawicz BJ, Coaker G. RIN4 functions with plasma membrane H+-ATPases to regulate stomatal apertures during pathogen attack. Plos Biology. 7: e1000139. PMID 19564897 DOI: 10.1371/journal.pbio.1000139

2008

Rentel MC, Leonelli L, Dahlbeck D, Zhao B, Staskawicz BJ. Recognition of the Hyaloperonospora parasitica effector ATR13 triggers resistance against oomycete, bacterial, and viral pathogens. Proceedings of the National Academy of Sciences of the United States of America. 105: 1091-6. PMID 18198274 DOI: 10.1073/pnas.0711215105

2007

Win J, Morgan W, Bos J, Krasileva KV, Cano LM, Chaparro-Garcia A, Ammar R, Staskawicz BJ, Kamoun S. Adaptive evolution has targeted the C-terminal domain of the RXLR effectors of plant pathogenic oomycetes. The Plant Cell. 19: 2349-69. PMID 17675403 DOI: 10.1105/tpc.107.051037

2006

Katiyar-Agarwal S, Morgan R, Dahlbeck D, Borsani O, Villegas A, Zhu JK, Staskawicz BJ, Jin H. A pathogen-inducible endogenous siRNA in plant immunity. Proceedings of the National Academy of Sciences of the United States of America. 103: 18002-7. PMID 17071740 DOI: 10.1073/pnas.0608258103

Mucyn TS, Clemente A, Andriotis VM, Balmuth AL, Oldroyd GE, Staskawicz BJ, Rathjen JP. The tomato NBARC-LRR protein Prf interacts with Pto kinase in vivo to regulate specific plant immunity. The Plant Cell. 18: 2792-806. PMID 17028203 DOI: 10.1105/tpc.106.044016

Day B, Dahlbeck D, Staskawicz BJ. NDR1 interaction with RIN4 mediates the differential activation of multiple disease resistance pathways in Arabidopsis. The Plant Cell. 18: 2782-91. PMID 17012600 DOI: 10.1105/tpc.106.044693

Coaker G, Zhu G, Ding Z, Van Doren SR, Staskawicz B. Eukaryotic cyclophilin as a molecular switch for effector activation. Molecular Microbiology. 61: 1485-96. PMID 16968222 DOI: 10.1111/j.1365-2958.2006.05335.x

Chisholm ST, Coaker G, Day B, Staskawicz BJ. Host-microbe interactions: shaping the evolution of the plant immune response. Cell. 124: 803-14. PMID 16497589 DOI: 10.1016/j.cell.2006.02.008

2005

Day B, Dahlbeck D, Huang J, Chisholm ST, Li D, Staskawicz BJ. Molecular basis for the RIN4 negative regulation of RPS2 disease resistance. The Plant Cell. 17: 1292-305. PMID 15749765 DOI: 10.1105/tpc.104.030163

Leister RT, Dahlbeck D, Day B, Li Y, Chesnokova O, Staskawicz BJ. Molecular genetic evidence for the role of SGT1 in the intramolecular complementation of Bs2 protein activity in Nicotiana benthamiana. The Plant Cell. 17: 1268-78. PMID 15749757 DOI: 10.1105/tpc.104.029637

Metz M, Dahlbeck D, Morales CQ, Al Sady B, Clark ET, Staskawicz BJ. The conserved Xanthomonas campestris pv. vesicatoria effector protein XopX is a virulence factor and suppresses host defense in Nicotiana benthamiana. The Plant Journal : For Cell and Molecular Biology. 41: 801-14. PMID 15743446 DOI: 10.1111/j.1365-313X.2005.02338.x

Chisholm ST, Dahlbeck D, Krishnamurthy N, Day B, Sjolander K, Staskawicz BJ. Molecular characterization of proteolytic cleavage sites of the Pseudomonas syringae effector AvrRpt2. Proceedings of the National Academy of Sciences of the United States of America. 102: 2087-92. PMID 15684089 DOI: 10.1073/pnas.0409468102

2004

Coppinger P, Repetti PP, Day B, Dahlbeck D, Mehlert A, Staskawicz BJ. Overexpression of the plasma membrane-localized NDR1 protein results in enhanced bacterial disease resistance in Arabidopsis thaliana. The Plant Journal : For Cell and Molecular Biology. 40: 225-37. PMID 15447649 DOI: 10.1111/j.1365-313X.2004.02203.x

2003

Axtell MJ, Chisholm ST, Dahlbeck D, Staskawicz BJ. Genetic and molecular evidence that the Pseudomonas syringae type III effector protein AvrRpt2 is a cysteine protease. Molecular Microbiology. 49: 1537-46. PMID 12950919 DOI: 10.1046/j.1365-2958.2003.03666.x

Banno S, Kimura M, Tokai T, Kasahara S, Higa-Nishiyama A, Takahashi-Ando N, Hamamoto H, Fujimura M, Staskawicz BJ, Yamaguchi I. Cloning and characterization of genes specifically expressed during infection stages in the rice blast fungus. Fems Microbiology Letters. 222: 221-7. PMID 12770711 DOI: 10.1016/S0378-1097(03)00307-0

Axtell MJ, Staskawicz BJ. Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4. Cell. 112: 369-77. PMID 12581526 DOI: 10.1016/S0092-8674(03)00036-9

2002

Jin H, Axtell MJ, Dahlbeck D, Ekwenna O, Zhang S, Staskawicz B, Baker B. NPK1, an MEKK1-like mitogen-activated protein kinase kinase kinase, regulates innate immunity and development in plants. Developmental Cell. 3: 291-7. PMID 12194859 DOI: 10.1016/S1534-5807(02)00205-8

Casper-Lindley C, Dahlbeck D, Clark ET, Staskawicz BJ. Direct biochemical evidence for type III secretion-dependent translocation of the AvrBs2 effector protein into plant cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 8336-41. PMID 12060777 DOI: 10.1073/pnas.122220299

Chang JH, Tai YS, Bernal AJ, Lavelle DT, Staskawicz BJ, Michelmore RW. Functional analyses of the Pto resistance gene family in tomato and the identification of a minor resistance determinant in a susceptible haplotype. Molecular Plant-Microbe Interactions : Mpmi. 15: 281-91. PMID 11952131 DOI: 10.1094/MPMI.2002.15.3.281

2001

Staskawicz BJ, Mudgett MB, Dangl JL, Galan JE. Common and contrasting themes of plant and animal diseases. Science (New York, N.Y.). 292: 2285-9. PMID 11423652 DOI: 10.1126/science.1062013

Chang JH, Tobias CM, Staskawicz BJ, Michelmore RW. Functional studies of the bacterial avirulence protein AvrPto by mutational analysis Molecular Plant-Microbe Interactions. 14: 451-459. PMID 11310732

Axtell MJ, McNellis TW, Mudgett MB, Hsu CS, Staskawicz BJ. Mutational analysis of the Arabidopsis RPS2 disease resistance gene and the corresponding pseudomonas syringae avrRpt2 avirulence gene. Molecular Plant-Microbe Interactions : Mpmi. 14: 181-8. PMID 11204781 DOI: 10.1094/MPMI.2001.14.2.181

Staskawicz BJ. Genetics of plant-pathogen interactions specifying plant disease resistance Plant Physiology. 125: 73-76. PMID 11154300 DOI: 10.1104/pp.125.1.73

2000

Gassmann W, Dahlbeck D, Chesnokova O, Minsavage GV, Jones JB, Staskawicz BJ. Molecular evolution of virulence in natural field strains of Xanthomonas campestris pv. vesicatoria Journal of Bacteriology. 182: 7053-7059. PMID 11092868 DOI: 10.1128/JB.182.24.7053-7059.2000

Orth K, Xu Z, Mudgett MB, Bao ZQ, Palmer LE, Bliska JB, Mangel WF, Staskawicz B, Dixon JE. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science (New York, N.Y.). 290: 1594-7. PMID 11090361

Mudgett MB, Chesnokova O, Dahlbeck D, Clark ET, Rossier O, Bonas U, Staskawicz BJ. Molecular signals required for type III secretion and translocation of the Xanthomonas campestris AvrBs2 protein to pepper plants. Proceedings of the National Academy of Sciences of the United States of America. 97: 13324-9. PMID 11078519 DOI: 10.1073/pnas.230450797

Keen N, Staskawicz B, Mekalanos J, Ausubel F, Cook RJ. Pathogens and hosts: The dance is the same, the couples are different Proceedings of the National Academy of Sciences of the United States of America. 97: 8752-8753. PMID 10922030 DOI: 10.1073/pnas.97.16.8752

Chang JH, Rathjen JP, Bernal AJ, Staskawicz BJ, Michelmore RW. avrPto enhances growth and necrosis caused by Pseudomonas syringae pv. tomato in Tomato lines lacking either Pto or Prf Molecular Plant-Microbe Interactions. 13: 568-571. PMID 10796023

Tai T, Staskawicz BJ. Construction of a yeast artificial chromosome library of pepper (Capsicum annuum L.) and identification of clones from the Bs2 resistance locus Theoretical and Applied Genetics. 100: 112-117.

1999

Gassmann W, Hinsch ME, Staskawicz BJ. The Arabidopsis RPS4 bacterial-resistance gene is a member of the TIR-NBS-LRR family of disease-resistance genes Plant Journal. 20: 265-277. PMID 10571887 DOI: 10.1046/j.1365-313X.1999.00600.x

Tai TH, Dahlbeck D, Clark ET, Gajiwala P, Pasion R, Whalen MC, Stall RE, Staskawicz BJ. Expression of the Bs2 pepper gene confers resistance to bacterial spot disease in tomato Proceedings of the National Academy of Sciences of the United States of America. 96: 14153-14158. PMID 10570214 DOI: 10.1073/pnas.96.24.14153

Rathjen JP, Chang JH, Staskawicz BJ, Michelmore RW. Constitutively active Pto induces a Prf-dependent hypersensitive response in the absence of avrPto Embo Journal. 18: 3232-3240. PMID 10369664 DOI: 10.1093/emboj/18.12.3232

Mudgett MB, Staskawicz BJ. Characterization of the Pseudomonas syringae pv. tomato AvrRpt2 protein: demonstration of secretion and processing during bacterial pathogenesis. Molecular Microbiology. 32: 927-41. PMID 10361296 DOI: 10.1046/j.1365-2958.1999.01403.x

Tobias CM, Oldroyd GED, Chang JH, Staskawicz BJ. Plants expressing the Pto disease resistance gene confer resistance to recombinant PVX containing the avirulence gene AvrPto Plant Journal. 17: 41-50. PMID 10069066 DOI: 10.1046/j.1365-313X.1999.00350.x

Tai T, Dahlbeck D, Stall RE, Peleman J, Staskawicz BJ. High-resolution genetic and physical mapping of the region containing the Bs2 resistance gene of pepper Theoretical and Applied Genetics. 99: 1201-1206. DOI: 10.1007/s001220051325

1998

Mudgett MB, Staskawicz BJ. Protein signaling via type III secretion pathways in phytopathogenic bacteria. Current Opinion in Microbiology. 1: 109-14. PMID 10438234

Aarts N, Metz M, Holub E, Staskawicz BJ, Daniels MJ, Parker JE. Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America. 95: 10306-10311. PMID 9707643 DOI: 10.1073/pnas.95.17.10306

McNellis TW, Mudgett MB, Li K, Aoyama T, Horvath D, Chua NH, Staskawicz BJ. Glucocorticoid-inducible expression of a bacterial avirulence gene in transgenic Arabidopsis induces hypersensitive cell death. The Plant Journal : For Cell and Molecular Biology. 14: 247-57. PMID 9628020 DOI: 10.1046/j.1365-313X.1998.00106.x

Oldroyd GED, Staskawicz BJ. Genetically engineered broad-spectrum disease resistance in tomato Proceedings of the National Academy of Sciences of the United States of America. 95: 10300-10305. DOI: 10.1073/pnas.95.17.10300

1997

Century KS, Shapiro AD, Repetti PP, Dahlbeck D, Holub E, Staskawicz BJ. NDR1, a pathogen-induced component required for Arabidopsis disease resistance. Science (New York, N.Y.). 278: 1963-5. PMID 9395402 DOI: 10.1126/science.278.5345.1963

1996

Swords KMM, Dahlbeck D, Kearney B, Roy M, Staskawicz BJ. Spontaneous and induced mutations in a single open reading frame alter both virulence and avirulence in Xanthomonas campestris pv. vesicatoria avrBs2 Journal of Bacteriology. 178: 4661-4669. PMID 8755898

Salmeron JM, Oldroyd GED, Rommens CMT, Scofield SR, Kim HS, Lavelle DT, Dahlbeck D, Staskawicz BJ. Tomato Prf is a member of the leucine-rich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster Cell. 86: 123-133. PMID 8689679 DOI: 10.1016/S0092-8674(00)80083-5

Scofield SR, Tobias CM, Rathjen JP, Chang JH, Lavelle DT, Michelmore RW, Staskawicz BJ. Molecular basis of gene-for-gene specificity in bacterial speck disease of tomato Science. 274: 2063-2065. DOI: 10.1126/science.274.5295.2063

1995

Rommens CMT, Salmeron JM, Baulcombe DC, Staskawicz BJ. Use of a gene expression system based on potato virus X to rapidly identify and characterize a tomato Pto homolog that controls fenthion sensitivity Plant Cell. 7: 249-257. PMID 7734960

Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD. Molecular genetics of plant disease resistance. Science (New York, N.Y.). 268: 661-7. PMID 7732374

Rommens CM, Salmeron JM, Oldroyd GE, Staskawicz BJ. Intergeneric transfer and functional expression of the tomato disease resistance gene Pto Plant Cell. 7: 1537-1544. PMID 7580250 DOI: 10.1105/tpc.7.10.1537

Century KS, Holub EB, Staskawicz BJ. NDR1, a locus of Arabidopsis thaliana that is required for disease resistance to both a bacterial and a fungal pathogen Proceedings of the National Academy of Sciences of the United States of America. 92: 6597-6601. DOI: 10.1073/pnas.92.14.6597

Hammond-Kosack KE, Staskawicz BJ, Jones JD, Baulcombe DC. Functional expression of a fungal avirulence gene from a modified potato virus X genome Molecular Plant-Microbe Interactions. 8: 181-185.

1994

Bent AF, Kunkel BN, Dahlbeck D, Brown KL, Schmidt R, Giraudat J, Leung J, Staskawicz BJ. RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes. Science (New York, N.Y.). 265: 1856-60. PMID 8091210

Salmeron JM, Barker SJ, Carland FM, Mehta AY, Staskawicz BJ. Tomato mutants altered in bacterial disease resistance provide evidence for a new locus controlling pathogen recognition Plant Cell. 6: 511-520. PMID 7911348 DOI: 10.1105/tpc.6.4.511

1993

Salmeron JM, Staskawicz BJ. Molecular characterization and hrp dependence of the avirulence gene avrPro from Pseudomonas syringae pv. tomato Mgg Molecular &Amp; General Genetics. 239: 6-16. PMID 8510663 DOI: 10.1007/BF00281595

Carland FM, Staskawicz BJ. Genetic characterization of the Pto locus of tomato: semi-dominance and cosegregation of resistance to Pseadomonas syringae pathovar tomato and sensitivity to the insecticide Fenthion Mgg Molecular &Amp; General Genetics. 239: 17-27. PMID 8510645 DOI: 10.1007/BF00281596

Long SR, Staskawicz BJ. Prokaryotic plant parasites Cell. 73: 921-935. PMID 8500181 DOI: 10.1016/0092-8674(93)90271-Q

Kunkel BN, Bent AF, Dahlbeck D, Innes RW, Staskawicz BJ. RPS2, an arabidopsis disease resistance locus specifying recognition of Pseudomonas syringae strains expressing the avirulence gene avrRpt2 Plant Cell. 5: 865-875. PMID 8400869

Innes RW, Bent AF, Kunkel BN, Bisgrove SR, Staskawicz BJ. Molecular analysis of avirulence gene avrRpt2 and identification of a putative regulatory sequence common to all known Pseudomonas syringae avirulence genes Journal of Bacteriology. 175: 4859-4869. PMID 8335641

Innes RW, Bisgrove SR, Smith NM, Bent AF, Staskawicz BJ, Liu YC. Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean Plant Journal. 4: 813-820. PMID 8275100

Whalen MC, Wang JF, Carland FM, Heiskell ME, Dahlbeck D, Minsavage GV, Jones JB, Scott JW, Stall RE, Staskawicz BJ. Avirulence gene avrRxv from Xanthomonas campestris pv. vesicatoria specifies resistance on tomato line Hawaii 7998 Molecular Plant-Microbe Interactions : Mpmi. 6: 616-627. PMID 8274773

Parker JE, Szabò V, Staskawicz BJ, Lister C, Dean C, Daniels MJ, Jones JDG. Phenotypic characterization and molecular mapping of the Arabidopsis thaliana locus RPP5, determining disease resistance to Peronospora parasitica Plant Journal. 4: 830-831.

1992

Ronald PC, Salmeron JM, Carland FM, Staskawicz BJ. The cloned avirulence gene avrPto induces disease resistance in tomato cultivars containing the Pto resistance gene Journal of Bacteriology. 174: 1604-1611. PMID 1537802

Bent AF, Innes RW, Ecker JR, Staskawicz BJ. Disease development in ethylene-insensitive Arabidopsis thaliana infected with virulent and avirulent Pseudomonas and Xanthomonas pathogens Molecular Plant-Microbe Interactions : Mpmi. 5: 372-378. PMID 1472714

1991

Whalen MC, Innes RW, Bent AF, Staskawicz BJ. Identification of Pseudomonas syringae pathogens of Arabidopsis and a bacterial locus determining avirulence on both Arabidopsis and soybean Plant Cell. 3: 49-59. PMID 1824334

1990

Kearney B, Staskawicz BJ. Widespread distribution and fitness contribution of Xanthomonas campestris avirulence gene avrBs2 Nature. 346: 385-386. PMID 2374611

Kearney B, Staskawicz BJ. Characterization of IS476 and its role in bacterial spot disease of tomato and pepper Journal of Bacteriology. 172: 143-148. PMID 2152895

1989

Huynh TV, Dahlbeck D, Staskawicz BJ. Bacterial blight of soybean: Regulation of a pathogen gene determining host cultivar specificity Science. 245: 1374-1377. PMID 2781284

Bonas U, Stall RE, Staskawicz B. Genetic and structural characterization of the avirulence gene avrBs3 from Xanthomonas campestris pv. vesicatoria Mgg Molecular &Amp; General Genetics. 218: 127-136. PMID 2550761 DOI: 10.1007/BF00330575

Lindgren PB, Frederick R, Govindarajan AG, Panopoulos NJ, Staskawicz BJ, Lindow SE. An ice nucleation reporter gene system: identification of inducible pathogenicity genes in Pseudomonas syringae pv. phaseolicola. The Embo Journal. 8: 1291-301. PMID 2548841

1988

Ronald PC, Staskawicz BJ. The avirulence gene avrBs1 from Xanthomonas campestris pv. vesicatoria encodes a 50-kD protein Molecular Plant-Microbe Interactions : Mpmi. 1: 191-198. PMID 2979910

Lindgren PB, Panopoulos NJ, Staskawicz BJ, Dahlbeck D. Genes required for pathogenicity and hypersensitivity are conserved and interchangeable among pathovars of Pseudomonas syringae Mgg Molecular &Amp; General Genetics. 211: 499-506. DOI: 10.1007/BF00425707

Kearney B, Ronald PC, Dahlbeck D, Staskawicz BJ. Molecular basis for evasion of plant host defence in bacterial spot disease of pepper Nature. 332: 541-543.

Tamaki S, Dahlbeck D, Staskawicz B, Keen NT. Characterization and expression of two avirulence genes cloned from Pseudomonas syringae pv. glycinea. J Bacteriol. 1988 Oct;170(10):4846-54. PMID: 3049552; PMCID: PMC211529. DOI: 10.1128/jb.170.10.4846-4854.1988.

Whalen MC, Stall RE, Staskawicz BJ. Characterization of a gene from a tomato pathogen determining hypersensitive resistance in non-host species and genetic analysis of this resistance in bean. Proc Natl Acad Sci U S A. 1988 Sep;85(18):6743-7. PMID: 16593982; PMCID: PMC282054. DOI: 10.1073/pnas.85.18.6743.

1987

Napoli C, Staskawicz B. Molecular characterization and nucleic acid sequence of an avirulence gene from race 6 of Pseudomonas syringae pv. glycinea. J Bacteriol. 1987 Feb;169(2):572-8. PMID: 3027035; PMCID: PMC211816. DOI: 10.1128/jb.169.2.572-578.1987.